Celebrex Action Mechanism
The main action mechanism of Celebrex to alleviate the pain and inflammation along with its wide range of symptoms that include tenderness, fever or swelling of joints is to block the production of prostaglandins. It causes this effect by impeding the function of cyclooxygenase-2 (COX-2) enzyme responsible prostaglandin production, which ultimately results in lowering of prostaglandin levels in body.
The normal dosage of Celebrex is 200mg per day (or 100mg twice a day) for alleviating the symptoms of osteoarthritis. Whereas, a dosage of 100mg - 200mg Celebrex is recommended twice a day for curing rheumatoid arthritis in adults.
The best of Celebrex is its minimal effect on stomach and intestine as well as its ability to not impede with clotting of blood along with effective pain killing ability made it a wonder drug.
One should avoid taking Celebrex if they are allergic to any of its ingredients or suffer from stomach ulcers, asthma, kidney or liver ailments, bleeding disorders, other stomach complications and hypertension. In case of recent surgery, pregnancy or breastfeeding conditions, kindly stay away from taking the help of Celebrex.
Celebrex Side effects
Some side effects of Celebrex that are generally observed include diarrhea, mild skin rash, dizziness, nervousness, stomach upset, flu symptoms such as sore throat and stuffy nose and headache.
Serious side effects of Celebrex that are reported in some extreme cases but require urgent medical help include loss of appetite, continuous itching sensation, shortness of breath, dark urine, numbness, coughing up of blood, chest pain, jaundice, rigorous skin reaction, clay colored stools and muscle pain or weakness.