Ibuprofen Action Mechanism
Ibuprofen inhibits synthesis of prostaglandins by hindering with the production of type 1 as well as type 2 cyclo-oxygenase enzymes. Inhibiting the function of COX-2 enzyme results in analgesic, anti-inflammatory and antipyretic activity of Ibuprofen whereas, COX-2 inhibition keeps platelet aggregation and GI mucosa inflammation away.
Dosage of Ibuprofen depends on your underlying condition and its severity such as to treat dysmenorrheal pain, a dose of 200 mg - 400 mg for every 4 to 6 hours is generally recommended. Whereas, to relieve the pain associated with rheumatoid arthritis as well as osteoarthritis 400mg - 800mg of Ibuprofen dosage for every 6 to 8 hours is prescribed.
Ibuprofen is not a master in one field itself but is also widely used as an anti-platelet factor as well as also posses the activity of vasodilator, which are its added special features.
In case you are allergic to any of its components, smoke, recently undergone surgery, drink alcohol, lactating mother or pregnant women than its better not take Ibuprofen medication. Also individuals with heart complications, diabetes, kidney or liver problems, asthma, hypertension, and stomach or bleeding troubles are not recommended Ibuprofen for mitigating their pain.
Ibuprofen Side effects
Common side effects of Ibuprofen found generally and that have mild effects on normal health include diarrhea or constipation, blurred vision, dizziness, itching or skin rash, headache and stomach distress.
While, serious side effects of Ibuprofen which were reported in some extreme cases include chest pain, jaundice, convulsions, severe tingling, bruising skin, muscle weakness, numbness and shortness of breath. These may require medical emergency if any of these effects persist for longer time.