Indapamide Action Mechanism
Indapamide stimulates the synthesis of hypotensive vasodilatory prostaglandin (PGE2) to obtain the desired effects. Antagonizing the activity of KCNE1 and KCNQ1proteins is the secondary effect of Indapamide medication.
The usual recommended dosage of Indapamide is to maintain the levels of salt and water and treat high blood pressure is 1.25 mg. Also 2.5 mg per day of Indapamide is recommended to treat edema generally found in congestive heart failure and is recommended to be taken in morning with water for effective results.
Indapamide not only works as an accurate and efficient diuretic medication but also works wonders in curing high blood pressure in individuals suffering with mild or severe real insufficiency.
Indapamide should never be taken during pregnancy, in case you are planning to get pregnant and breastfeeding. While in case you have unusual or allergic reaction to any of its active or inactive components or suffer from gout, kidney ailments, electrolyte or fluid complications and diabetes than its best not to take Indapamide.
Indapamide Side effects
The common but mild side effects of Indapamide include loss of appetite, nausea or vomiting, headache, diarrhea, stomach complication and abdominal pain.
While serious side effects of Indapamide include irregular heartbeat, blurred vision, weakness or tiredness, restlessness, dry mouth, flu like symptoms, muscle cramps or spasm, anxiousness, severe allergic manifestations and redness or loosening of skin.