Paracetamol Action Mechanism
Although the mechanism of action of Paracetamol is not clearly understood it is found to carry out its action by impeding prostaglandin synthesis in nervous system. Paracetamol acts on the temperature-regulating centre of brain to keep your temperature under control.
The recommended dosage of Paracetamol to lower your raised temperature is between 325 mg - 650 mg which should be taken orally for every 4 to 6 hours. While in case you aim for better mode of administration than 1000 mg for every 6 to 8 hours should be taken rectally. And most importantly it is available only through prescription.
The ability of Paracetamol to produce the desired results in short span of time along with its outstanding safety and efficacy profile made it the most preferred pain reliever medicament.
Women who are planning to become pregnant or are going through pregnancy and lactating mothers are not recommended to take Paracetamol. Also individuals allergic to this medication, alcoholic and suffering with deficiency of glucose-6-phosphate dehydrogenase enzyme (G6PD), phenylketonuria (PKU), diabetes and liver or kidney impairment should never take the aid of Paracetamol.
Paracetamol Side effects
Common but mild side effects of Paracetamol include nausea or vomiting, stomach pain, headache and stomach upset.
While serious side effects of Paracetamol include unusual bruising or bleeding, fever, change in amount of urine expelled or difficulty in passing urine, breathing problems, yellowing of skin or eyes, unusual tiredness or weakness, sore throat and severe allergic reactions such as skin rash, itching or hives and swelling of face, lips or tongue.